Exploring Stereotypes and Cultural References in Dubbed TV Comedies in the Spanish-as-a-Foreign-Language Classroom

Streaming video-on-demand (SVoD) platforms have recently set out to produce an ever-increasing number of non-English-language films and tv series distributed worldwide. These, in turn, have become the perfect vehicle for disseminating cultural realities other than those from English-speaking countries. In this article, we endeavour to analyse the presence of stereotypes and cultural references in the English-dubbed version of the Spanish tv series Valeria (Benítez, 2020–present) and the way they travel through dubbing. To this end, we conducted a comparative study in which seven video excerpts from the English-dubbed version and their original Spanish version were shown to 57 native English-speaking participants from a British higher education institution, who shared a similar knowledge of Spanish as a foreign language. Specifically, we explored the participants’ overall perception of humorous passages, their identification of cultural references, their informed opinion on the translation techniques applied (and alternatives given), and their self-assessment of the metacognitive effort required. TThe findings show two aspects of learners: (a) overall, these learners were eager to maintain stereotypes and cultural references used for humorous purposes in audiovisual comedies, and (b) their understanding of these items often relies on audiovisual support. The findings offer an initial examination of English speakers’ cognitive and evaluative perception of Spanish comedies that have been dubbed in English and can be useful for translator training purposes

Bronchopulmonary infection-colonization patterns in Spanish cystic fibrosis patients: Results from a national multicenter study

Background: Clinical and demographical knowledge on Spanish cystic fibrosis (CF) patients is incomplete as no national registry exists. CF-microbiology has not been studied at national level. The results of the first Spanish multicenter study on CF microbiology are presented.Methods: 24 CF-Units for adult (n = 12) and pediatric (n = 12) patients from 17 hospitals provided sputa and clinical data from 15 consecutive patients. Cultures and susceptibility testing were performed. Colonization impact on pulmonary function was assessed.Results: 341 patients [mean (SD) age 21 (11) years, 180 >= 18 years, mean (SD) FEV1 = 68 (25)%] were included. Pseudomonas aeruginosa was reported as chronic, intermittent or absent in 46%, 22% and 32% of patients, respectively. The annual prevalence was 62%. Positive P. aeruginosa and methicillin-resistant Staphylococcus aureus cultures were significantly associated with lower FEV1 (p = 18 years, mean (SD) FEV1 = 68 (25)%] were included. Pseudomonas aeruginosa was reported as chronic, intermittent or absent in 46%, 22% and 32% of patients, respectively. The annual prevalence was 62%. Positive P. aeruginosa and methicillin-resistant Staphylococcus aureus cultures were significantly associated with lower FEV1 (

Heterozygous pathogenic variants in GLI1 are a common finding in isolated postaxial polydactyly A/B

Postaxial polydactyly (PAP) is a frequent limb malformation consisting in the duplication of the fifth digit of the hand or foot. Morphologically, this condition is divided into type A and B, with PAP-B corresponding to a more rudimentary extra-digit. Recently, biallelic truncating variants in the transcription factor GLI1 were reported to be associated with a recessive disorder, which in addition to PAP-A, may include syndromic features. Moreover, two heterozygous subjects carrying only one inactive copy of GLI1 were also identified with PAP. Herein, we aimed to determine the level of involvement of GLI1 in isolated PAP, a condition previously established to be autosomal dominantly inherited with incomplete penetrance. We analyzed the coding region of GLI1 in 95 independent probands with nonsyndromic PAP and found 11.57% of these subjects with single heterozygous pathogenic variants in this gene. The detected variants lead to premature termination codons or result in amino acid changes in the DNA-binding domain of GLI1 that diminish its transactivation activity. Family segregation analysis of these variants was consistent with dominant inheritance with incomplete penetrance. We conclude that heterozygous changes in GLI1 underlie a significant proportion of sporadic or familial cases of isolated PAP-A/B